Exact(5)
We found that 10 μg/ml was an adequate protein concentration to form uniform layer, and higher concentration may cause protein aggregation.
Since dynein is required for autophagic clearance (Maday et al., 2012; Kimura et al., 2008; Ravikumar et al., 2005), dynein malfunction may cause protein aggregation and mitochondrial dysfunctions, and result in neuronal atrophy.
25.0% (in Populus) and 26.8% (in Eucalyptus) of the AS events may cause protein domain modification.
Hydrophobic interactions make non-polar side chains to pack together inside proteins, and disruption of these interactions may cause protein destabilization.
Other studies have shown that the intrusion of lead into the lens of the eye may cause protein conformational changes that decrease lens transparency.
Similar(55)
Recent evidence shows that chronic inflammation may cause protein-energy malnutrition and progressive atherosclerosis in HD patients [ 6].
Malnutrition is associated with an increased risk of cardiovascular death and may cause protein-energy wasting in individuals with chronic kidney disease.
Since malnutrition may cause protein-energy wasting and is associated with increased risk of mortality in ESRD patients [ 14, 15], it seems reasonable to imply that environmental cadmium exposure may influence the nutritional status and survival of CPD patients.
Hydrophobicity changes owing to amino acid substitutions may cause proteins not to fold into stable conformation, and thus result in protein destabilization.
CuAO production of formaldehyde has also been implicated in the alteration of protein structure, which may subsequently cause protein deposition associated with chronic vascular and neurobiological disorders, such as diabetic complications, atherosclerosis, and neurodegenerative disease (7, 14).
First, the regulation of translation or of protein turnover rate may cause the protein abundance to not be proportional to mRNA abundance.
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