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Oxygen deficiency during critical illness may cause profound changes in cellular metabolism and subsequent tissue and organ dysfunction.
Movement of landslides in this area may cause profound impact and damages.
Meanwhile, Baiyun Depression is located at Zhujiangkou Basin, an area with relatively mature development of hydrocarbon in China (Jiang [2009]); a submarine landslide occurs in this area may cause profound impact and damages.
Strokes that occur in the brainstem may cause profound deficits, including locked-in syndrome, in which cognitive, emotional and linguistic abilities remain intact but all or almost all voluntary motor abilities are lost.
The Australian Medical Board's official position is that: "A breach of sexual boundaries is unethical and unprofessional because it exploits the doctor-patient relationship, undermines the trust that patients (and the community) have in their doctors and may cause profound psychological harm to patients and compromise their medical care".
Even small doses may cause profound hypotension.
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This may eventually cause profound physical and ecological shifts regionally, and maybe continent-wide.
As a negative counterpart in VEGF signaling, elevation of sVEGFR1 will lead to an anti-inflammatory state; however, uncontrolled elevation of sVEGFR1 may also cause profound immune depression and lead to a worse outcome in patients with septic shock.
Much evidence suggests that antibiotics may cause a profound imbalance within the intestinal microbiota [ 5] and lead to complications.
Oral and orofacial problems may cause a profound impact on children's oral health-related quality of life (OHRQoL) because of symptoms associated with these conditions that may influence the physical, psychological and social aspects of their daily life.
Thus, our hypothesis is that an increased production of ROS due to the effect of pro-inflammatory mediators may cause a profound inhibition of the oxidative phosphorylation system leading to a compensatory "hypertrophy" of its components.
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CEO of Professional Science Editing for Scientists @ prosciediting.com