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Heavy metals viz., cobalt and copper are extremely essential to humans, but if present in large quantities may cause physiological disorders.
Thus inflammation, oxidative stress and endothelial dysfunction in healthy aging may cause physiological vulnerabilities favoring the appearance of new diseases.
Such mechanisms underlying these phenomena may cause physiological differences in subjects with SAR, leading to alterations in the epithelial milieu that favor particular organisms or sets of organisms.
In analogy to the experimentally deleted C/EBPβ uORF initiation codon in C/EBPβΔuORF mice, naturally occurring uORF mutations in other genes may cause physiological alterations by deregulating translation of the affected transcript.
Plants can synthesize riboflavin while the levels vary widely in different organs and during different stages of development, suggesting that changes in riboflavin levels may cause physiological effects [ 2, 4, 5].
For these physiological effects, as with blood pressure, a number of external factors can influence levels or performance, but the observation that serum PCB levels can influence them indicates that PCB levels may cause physiological changes and contribute to the development of diseases even when they are not the sole cause.
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Ascaris lumbricoides (A. lumbricoides) and Trichuris trichiura (T. trichiura) may also cause physiological abnormality of the intestinal wall leading to reduced food intake and nutrient absorption [ 10, 11].
Interaction of nanoparticles with organisms may cause various physiological and biochemical changes, both positive and negative.
Meaning the lowered variety in alleles and change in selection pressures may cause other physiological cost to the organisms.
In particular ephemeral macroalgal mats, which severely restrict water exchange, may cause significant physiological stress to understorey corals.
Induced hypothermia may cause various physiological changes as well as adverse events (AEs) [ 14, 15].
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