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FA may cause molecular damage to plant cells either directly or indirectly through the formation of ROS, which include free radicals as well as non-radical molecules of high reactivity.
For SEM, since the chamber is at high vacuum, plant specimen is normally required to be fully dehydrated by chemical fixation, which may cause molecular denaturation and structure artifact.
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It is well-known that excipients are promoters of degradation more than stabilizers of drug substances, but their role depends on all factors that may cause the molecular transformation of the drug, including the interaction between molecules adjacent to the API, as is often the case with impurities and excipients [43], [44].
The heterogeneity of head and neck tumors in combination with HPV infection may cause complex molecular perturbations in the cell and differences in survival and migration pathways that are affected may affect chemotherapy or radiation resistance and therefore prognosis of HPV-positive vs. HPV-negative SCCHN.
The presence of even short-lived reactive species can cause molecular changes that may degrade molecular species that are necessary for the chemical and/or physical stability of the system, or can cause the production of toxic byproducts from dispersants.
Insufficient crosslink reversal may cause multiple higher molecular weight bands in addition to the specific signal.
These measures provide a way in which to examine the different processes that may cause rates of molecular evolution to co-vary with clade size.
Because the DNO and NR were labeled with fluorescent Cy5 oligonucleotides, we were able to examine via AGE if low divalent cation conditions may cause a loss of molecular cargo attached to the nanostructures.
Our observations indicate instead, that exacerbated immune response of the wax moth induced by increased exposure of PAMPs (pathogen-associated molecular patterns) may cause self-damage that results in increased mortality of larvae infected with the color mutants.
The combination of routine exposure of the cornea to UV-radiation and molecular oxygen may cause excessive production of reactive oxygen species (ROS), leading to substantial oxidative stress and subsequent tissue damage [1].
We suggest that this molecular mechanism may cause genetic disease much more frequently than reported so far.
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