The lesion may cause either insufficiency of the valve, preventing it from operating in a normal fashion and leading to regurgitation, or stenosis (narrowing) of the valve, preventing a normal flow of blood and adding to the burden of the heart.
In contrast, discontinuing vascularity by cutting, suturing or coagulating vessels may cause vascular insufficiency.
It is well known that etomidate may cause adrenal insufficiency.
However, multiple steroid cycles may cause adrenal insufficiency or osteoporosis in mothers [49].
The end-stage of renal disease, chronic hemodialysis, and transplantation failure may cause multiorgan insufficiency, metabolic imbalance, and a high risk of postoperative complications and mortality.
This supports that conventional Le Fort I osteotomy increases velopharyngeal space and may cause velopharyngeal insufficiency but Zisser's osteotomy does not.
If altered nutrient-sensing pathways, lipotoxicity, and organelle dysfunction in kidneys under excess nutrient stresses are involved in the pathogenesis of renal diseases, a high energy intake along with a low-protein diet may cause an insufficiency of protein restriction in the treatment of diabetic nephropathy.
Delayed initiation of breastfeeding and technical problems in nursing may cause maternal milk insufficiency and increase the risk of hyperbilirubinemia [ 2].
The use of etomidate as the sedative agent in this context has been challenged because it may cause a reversible adrenal insufficiency, potentially associated with increased in-hospital morbidity.
Moreover, it has been described that in addition to AP instability, PCL insufficiency may cause (anterior knee) pain and result in malfunction (Waslewski et al. 1998, Pagnano et al. 1998).
