Sentence examples for may cause inactivation from inspiring English sources

We conducted an analysis of fine constitutions and properties to determine the presence of any inhibitory components that may cause inactivation or otherwise hinder the hydrolysis of cellulose in these fines.

Furthermore, it seems plausible that ischemia-induced depolarization may cause inactivation of voltage-gated K+ channels that normally dominate presynaptic spike repolarization [56] [58], thus allowing more BK channels to activate and dominate the repolarization [48], [59].

Thus, p53-dependent upregulation of PTEN may cause inactivation of mTOR with a temporary neuroprotective effect.

It is suggested that low levels of ROS may reversibly increase SERCA activity, whereas higher levels may cause inactivation as a result of irreversible oxidative modifications [134,137].

This suggests that the H435P substitution may cause inactivation of PLCζ due to the introduction of major protein structural changes, consistent with that proposed previously [ 13].

Furthermore, it is thought that the acidic degradation products of PLGA may cause inactivation of the protein-based NGF creating a concern for the maintenance of NGF stability and ultimate bioactivity [ 53, 88, 124].

In addition, intragenic mutation and loss of heterozygosity (LOH) at the Smad4 locus has been reported in many tumors, although these genetic alterations may not directly cause inactivation of Smad4 in some cancers [ 61- 63].

Additionally, we and other teams have verified that AMPK may cause an inactivation of NFκB by phosphorylating protein phosphatase 2A (PP2A) or Sirtuin 18,32,33.

We hypothesize that switching may cause the inactivation gate to remain fully open and that PIEZO1 undergoes a conformational change that allows the channel to respond directly to voltage.

It has also been reported that chromothripsis, a massive genomic rearrangement in a single catastrophic event, at the RB1 locus may cause gene inactivation [13].

Expression of miR-143 was restored by 5-aza-2′-deoxycytidine treatments (Fig. S3a), suggesting that DNA methylation may cause transcriptional inactivation of miR-143 in GC cells.