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The consistent expression changes that we observed in the genes of the affected regions, may cause imbalances in the regulation of many pathways.
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Inappropriate scaling may cause imbalanced penalty on linear coefficients.
Baseline imbalance, when small arm denominators may cause imbalance between arms in important prognostic factors (e.g. baseline performance).
This observation suggests that sharing a placenta may cause imbalanced in utero conditions and, consequently, more discordant epigenetic profiles.
An abnormal change in one Hilit may cause imbalance among the Hilits, leading to the development of a syndrome.
Moreover, SNPs in non-protein coding regions of genes that affect binding of regulatory factors may cause imbalanced expression of SNP alleles.
Obesity in E2 and progesterone deprived states in postmenopausal women may cause imbalance in homeostasis and changes in epithelial cells, stromal cells and adipocytes in the breasts that promote the growth and survival of receptor positive breast cancer cells.
Metabolic insulin resistance is characterized by pathway-specific impairment in PI 3-kinase dependent signaling induced, e.g., by proinflammatory cytokines (tumor necrosis-α [TNF-α], interleukin [IL]-1β, IL-6, C-reactive protein [CRP]), which in the endothelium may cause imbalance between production of NO and glucose uptake, resulting in insulin resistance and endothelial dysfunction.
These cells are still affected by hormone changes and may cause hormonal imbalances.
In other words, excessive reliance on low meat or high vegetable intake may cause nutritional imbalances and increase the fracture risk in such a population.
These may cause electrolyte imbalances.
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