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Exact(17)
Fragmentation may cause genetic isolation by next generations, increasing differentiation among populations.
Nano-TiO2 particles may cause genetic toxicity through changing the structure of molecular complex and the permeability of cell membrane [13 15].
Manned mission to space has been threatened by various cosmos risks including radiation, mirogravity, vacuum, confinement, etc., which may cause genetic variations of astronauts and eventually lead to damages of their health.
However, the driving force that may cause genetic differentiation in weedy rice have rarely been discussed or explored.
It is believed that long-term inflammation due to gastro-esophageal reflux may cause genetic and epigenetic alterations in Barrett's esophagus, and that accumulation of these genetic and epigenetic alterations would lead the acquisition of malignant characteristics in the Barrett's cells, such as dysregulated cell proliferation, impaired apoptosis, and angiogenesis.
We suggest that this mechanism may cause genetic disease much more frequently than previously reported.
Similar(43)
Moreover, integration of exogenous pluripotent transcription factors into the genome may also cause genetic variations in iPSCs.
Mutations within other splice elements, such as the polypyrimidine tract and the branch point, may also cause genetic diseases through the exclusion of a constitutive exon from the mature mRNA (6), but these are less frequent.
Compounds capable of initiating tumour development may act directly to cause genetic damage, or they may require metabolic conversion by an organism to become reactive.
If a gene bearing a mutation is passed on, it may cause a genetic disorder.
CRISPR DNA editing may cause serious genetic damage, researchers warn.
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