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Exact(7)
Alternative splicing affects up to 74% of all genes and may cause epigenetic instability when aberrant [ 3].
Inhibition of histone deacetylase activity results in increased protein acetylation and acetylation of histones may cause epigenetic gene modulation that induce differentiation and apoptosis in AML cells.
Recent epidemiological studies have provided evidence suggesting that environmental factors may cause epigenetic alterations affecting both the mother and her child [ 53].
A reduction in mR-224 expression may cause epigenetic regulation of CRC metastasis through targeting Cdc42 and may be considered as a potential predictive biomarker for CRC progression.
FASD may cause epigenetic changes due to reduced SAM and aberrant DNA methylation that could affect health [reviewed in Smith (4)].
This may affect fetal programming through immunomodulation [ 5], and perinatal anxiety may cause epigenetic changes in the offspring leading to an increased vulnerability to neurodevelopmental diseases in later life [ 6].
Similar(53)
OCs may also cause epigenetic changes, such as a decrease in DNA methylation [ 53].
A new study provides further evidence 1,3-butadiene may indeed cause epigenetic damage [ EHP 119 5):635 640; Koturbash et al.].
The cascade nature of epigenetic regulation may cause individual epigenetic modifications to be somewhat redundant as markers of the epigenetic state, and this might facilitate an overall understanding of coordinated regulation of gene expression in cancer and facilitate identification of molecular targets of cancer therapy.
In plants, for example, exposure to stressful UV-light may cause an epigenetic trace which is maintained in many generations of offspring growing under non-stressful conditions [5].
Any outside stimulus that can be detected by the body has the potential to cause epigenetic modifications.
More suggestions(15)
may demonstrate epigenetic
may change epigenetic
may control epigenetic
may cause particular
may cause unwanted
may modify epigenetic
may inhibit epigenetic
may reprogram epigenetic
may involve epigenetic
may escape epigenetic
may cause serious
may cause unnecessary
may require epigenetic
may modulate epigenetic
may cause civil
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