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Exact(27)
A parameter range outside biological condition may cause endothelial injury which is the main source of human mortality (Tada et al. 2007).
The systemic inflammatory response may cause endothelial injury and vascular dysfunction, although the exact mechanisms of how this occurs remain to be determined.
The denatured ECM may cause endothelial dysfunction by mechanotransduction mechanisms.
Recently, Arcano et al. [ 28] reported that insulin may cause endothelial dysfunction in humans.
Elevated blood pressure may cause endothelial dysfunction, leading to opening of the BBB [ 54].
An uncontrolled diabetes mellitus may cause endothelial dysfunction through additional mechanisms apart from adiponectin signaling.
Similar(33)
However, rheumatoid factor may directly cause endothelial injury [ 31].
Thus, insulin may also cause endothelial dysfunction through increased endothelin-1 availability and through downstream effects on NAD(P H oxidase and superoxide anion production.
Recent studies have demonstrated that cytokines – mediators of inflammatory response-may cause endothelial dysfunction through different mechanisms such as oxidative stress [ 3] and endothelial cell damage [ 4].
Objectives Coronary arterial lesions after Kawasaki disease (KD) may cause coronary endothelial dysfunction as the result of intimal hypertrophy.
These data demonstrate that PM2.5 exposure may cause immediate endothelial dysfunction.
More suggestions(15)
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