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While endocrinologically inert ovarian tumors are associated with morphologic evidence of stromal activation, endocrinologically active ovarian tumors may cause differentiation along either male or female lines as a consequence of differential productions of androgens and estrogens.
This altered cell alignment may cause differentiation defects in neuronal tissues.
Based on the alterations of hematopoietic cell differentiation markers, TERT deficiency in zebrafish may cause differentiation and maturation failure in both primitive and definitive hematopoiesis.
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It has been suggested that Dp53 expression may also cause differentiation defects.
The chromosomal translocations encode abnormal fusion proteins, usually transcription factors whose altered properties may cause the "differentiation arrest".
However, the driving force that may cause genetic differentiation in weedy rice have rarely been discussed or explored.
Overall, DISC1 dysfunction may cause impaired differentiation of oligodendrocytes by affecting Sox10 and/or Nkx2.2 expression and consequently contribute to the pathophysiology of psychiatric disorders.
Data accumulated here suggest that activation of the NF-κB pathway in DPSCs from different species may cause distinctive differentiation potency via different upstream and downstream signaling pathways.
In combination with medaka data, male germ cells with DNA damage may cause trans-differentiation into female-type meiosis, if they were not eliminated by apoptosis.
The decay of radioactive isotopes may not have produced sufficient heat to cause differentiation.
Fisheries-induced selection can cause differentiation of Pan I among local groups and using that differentiation to argue for local population structure and special management of local populations may be circular.
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