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Dr. Cummings suspects that the loss of estrogen may cause cells in other parts of their body to atrophy as well, perhaps accelerating cardiovascular decline or degenerative conditions like Alzheimer's disease.
Extended hypotonic challenge may cause cells to release ions and osmolytes, resulting in a slow volume decrease, which is called regulatory volume decease (RVD).
Although by no means definitive, there is some evidence that suggests that desmosome assembly may cause cells to undergo EMT reversal, the so-called 'mesenchymal epithelial conversion'.
Increased activity of β-galactosidase (a lysosomal enzyme) is associated to auto lysosomal activity, which may cause cells to undergo ageing and finally death [ 39].
The differential uptake of ACD may cause cells to react to drugs differently and ultimately result in alterations of nucleotides pools in each cell to varying degrees.
DNA damage interferes with vital processes such as transcription and replication, which may cause cells to die or senesce, thus contributing to aging [ 3].
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Ionizing radiation, on the other hand, has the ability to alter atoms, which is what may cause cell damage.
Among the environmental perturbations that may cause cell necrosis are oxygen deprivation (anoxia), hyperthermia, immunological attack, and exposure to various toxins that inhibit crucial intracellular metabolic processes.
DRG microinjection may cause cell damage although the injected DRGs retained their structural integrity and displayed no significant changes in the numbers of neurons or satellite cells (data not shown).
To evaluate whether chronic CNO administration may cause cell death of CA3 pyramidal neurons, we used terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL) assay to assess the extent of apoptotic death.
The addition of cryopreservative agents (CPAs) to chondrocytes and natural and engineered cartilage is critical to protect the cells and tissues from freezing damage during cryopreservation, but this may cause cell damage, e.g. by osmotic shock.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com