Toxicity responses broadly vary among individuals of different species.
For example, detection and screening practices in NA are more aggressive than in EU, which may explain, in part, why the NA patients are diagnosed with prostate cancer younger and have lower PSA levels than EU patients 9. Treatment patterns also differ, as do the treatment guidelines in use in each region 10– 15, to which general adherence and interpretation may also vary broadly.
This decision may vary broadly according to countries and to physicians characteristics [3].
The time course of the asthmatic crisis as well as the severity of airways obstruction may vary broadly [ 14].
Our study also makes the point that even so-called housekeeping genes, although quite broadly expressed, may vary significantly among tissues in levels of expression.
Moreover, the contribution of point mutations may vary broadly both in terms of the derived trade-off between promiscuous and primary activities [ 12, 13] and their closeness to the active site of enzymes [ 14, 15].
In addition, costs of a dengue episode may vary broadly from one health facility to another depending on how well the health equity funds operate – User-fees exemption for the poor shown in some Cambodian hospitals could worsen inequity [ 9, 16].
Hence, while many basic intestinal cell characteristics are likely to be broadly conserved, other characteristics may markedly vary among different nematode lineages and species.
Not only would such analysis test the importance of risk factors previously identified, but it may also reveal the importance of factors that are broadly homogeneous within countries but may vary across countries.
In addition, the hypoxia-tolerant and hypoxia-sensitive phenotypes are broadly defined and their expression may vary from one human tumour to another.
