Sentence examples for may block viral from inspiring English sources

While chemokines may block viral entry by binding to CCR5 and contribute to endogenous anti-HIV activity, increases in their expression may paradoxically facilitate infection by increasing target cell availability.

Thus, the NS3-4A protease is a dual therapeutic target, whose inhibition may block viral replication and restore IRF-3 control of HCV infection.

The results of the SPR, immunoprecipitation, and immunohistochemistry analyses of HSV-2 combined suggest that GRFT may block viral entry by binding to HSV-2 glycoprotein D. Cell-based assays suggest anti-HPV activity through α6 integrin internalization.

Our study provided an interesting hypothesis concerning the miRNA-based antiviral defense mechanism against influenza virus in human, i.e., the binding between human miRNA and viral RNAs may not result in gene silencing but rather may block the viral RNA replication.

HA is crucial to viral infection because it binds to sialidated cell-receptors and mediates fusion of cell and viral membranes; because antibodies that bind to HA may block virus entry to the cell, this protein is subjected to high selective pressure.

Merely blocking cell binding may therefore not suffice to block viral transmission.

Therefore, eliciting antibodies against MPER by vaccination may disturb its function thus effectively block viral entry and protect humans from HIV-1 infection.

This implied that the Phyllanthus extract may be blocking viral adsorption into the Vero cells [ 35].

Although the receptors for some viruses have not been clearly defined, the sites in the spike proteins of these viruses for binding to the cellular cofactors that facilitate viral entry may also be used to design vaccines able to induce antibodies to block viral entry or neutralize viral infectivity.

For an effective HCV vaccine, a T-cell response targeting multiple epitopes may be required to limit the possibility of viral escape and to effectively block viral replication [45,96,97].

Those Abs could block viral binding to the sialic acid receptors on cell surface (Skehel and Wiley, 2000).