"We now have a mass of cells that may have the potential to become various tissue types, and, ultimately, organs," says Atala. "At this stage one may take the cells and drive them to become different tissue types genetically identical to the patient's own tissue.
Upon swelling in a solvent, a thin hydrogel layer on a rigid substrate may become unstable, developing various surface patterns.
Because a new technology may become available at various points in time during the BART analysis process, we believe that guidelines are needed on when a technology must be considered.
As a consequence, malignant cells may become insensitive to various anti-cancer drugs.
The actin cytoskeleton is highly dynamic, constantly being remodelled in living cells and may become dysfunctional in various kidney diseases, including diabetic nephropathy (DN) [ 1- 4].
Biopharmaceuticals may become exposed to various conditions of stress, such as low pH or heat, which can potentially result in protein misfolding and the formation of amyloid-like structures [ 62].The mechanisms by which different culture, formulation and storage conditions affect the physical stability of proteins are an active area of research.
Taken together, all this further strengthens the notion that autophagic and endolysosomal trafficking pathways cannot be perceived as autonomous, physically separate entities, but rather as two functional components of an integrated cellular system, the balance of which in AD may become compromised at various levels and in relation to many different factors.
Annotations that are accurate at the time of their creation may become 'stale' for various reasons: if the GO structure changes, for example if a new, more granular term is added that is appropriate to the gene product; or if new characterization of a gene product means that a previously annotated role is seen to be indirect or is proven to be untrue.
AST may become elevated in response to various forms of stress in several different taxa, and most of the literature indicates that Hg exposure may also elevate plasma AST levels (Adachi et al. 1996; Hoffman et al. 2005).
POTAMON can be useful to explore plankton dynamics in a large river, and it may become a tool to test various management measures.
