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This will lead to artifactual mismatches between wild type and 'slippage' strands, which may become substrates for the Cel1 nuclease.
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The specific features of the mRNAs may affect how they become substrates for NSD or other mRNA quality control pathways.
Such misfolded RNA may become a substrate for nucleases, thereby rendering it unstable.
In addition, the dismutation of superoxide radicals releases molecular oxygen that may become a substrate for the Aβ-dependent production of H2O2 (Fig. 8).
Instead, these partially resected ends become substrates for MMEJ.
A limitation of substrate activation approach is that the activated substrates may become chemically unstable or undergo some undesired side reactions.
(iv) The sputtering of a supported NP is a complex situation; on the one hand, energy can dissipate from the NP to the substrate decreasing the NP sputter yield; on the other hand, also the substrate may become sputtered and lead to a secondary sputtering of the NP.
As glycerol is a renewable resource, obtaining fumaric acid from glycerol as substrate may become economically attractive.
As composting begins, large organic molecules are broken down to smaller soluble structures and temporarily more substrate may become available.
Upon swelling in a solvent, a thin hydrogel layer on a rigid substrate may become unstable, developing various surface patterns.
The straplike or platelike protonema (the structure that produces the sexual plant by budding) provides firm attachment to the rock substrate and may become dormant in unfavourable conditions.
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