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These exciting results provide the first evidence that RyR calcium signaling plays an essential role in the development of hypoxic PAH, and also suggest RyR antagonists that are available and even used in clinic may become potentially new and effective therapeutics to treat PAH and other relevant pulmonary vascular diseases in the future.
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Because the point spread function (PSF) images recorded by the double-pass instrument can be affected by high-frequency noise, which is inherent in the use of cameras, the frequency for very small MTF values may become unstable, potentially leading to artifacts.
Mercury-in-glass thermometers may no longer be available; and if broken, become potentially toxic to patient and environment.
There are few leishmanicidal agents for the current leishmaniasis clinical therapy; in addition, visceral leishmaniasis may affect the liver and spleen and can become potentially lethal.
And it may become subject to potentially tougher rules governing its capital, affecting its ability to continue buying back stock.
Respiratory syncytial virus is a worldwide pathogen agent responsible for frequent respiratory tract infections that may become severe and potentially lethal in high risk infants and adults.
Likewise, disease-specific DPCO models may become available that potentially allow informing an efficacy model across different drugs, as was demonstrated for colorectal cancer.
Tells about the threat to Israeli democracy by the Begin govt. Some fear Israel may become an aggressive and potentially totalitarian nation.
Second, if the driver is disabled by the shot, the vehicle may become unguided, making it potentially more dangerous," the agency wrote in a 2014 summary of an investigation into the Cleveland Police Department's use of force.
If the oceans warm sufficiently through global warming, the methane on the ocean floor may become unstable, instigating a potentially catastrophic positive feedback to global warming (between the Triassic and Jurassic periods, about half of all life on earth went extinct, probably due to this drastic and sudden climate change).
Despite the stability of these parameters, patients may become conscious during surgery, potentially leading to explicit memory of words spoken in the operating room, discomfort, or pain.
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CEO of Professional Science Editing for Scientists @ prosciediting.com