Sentence examples for may be substrates from inspiring English sources

However, type I survivors also showed a high propensity for conversion to type II survivors, suggesting that telomeres in the absence of telomerase may be substrates for several different types of recombination events.

For Dkk2, 3 and -4 significant amounts of smaller MW proteins are observed in SDS PAGE, indicative of proteolytic processing, which probably occurs at the various dibasic cleavage sites that Dkk proteins harbor and which may be substrates for Furin type proteases.

Considering that the prevalence of insomnia among individuals with migraine is much higher than that among those with TTH, our findings indicate that migrainous features may be substrates for the development of insomnia among individuals with TTH [9, 10, 25].

A key feature is that different antimicrobial classes may be substrates of a single pump: exposure to a given class (e.g., beta-lactams) may thereby select mutants with resistance to other classes (e.g., beta-lactams plus fluoroquinolones or aminoglycosides) [95].

As several biologically effective compounds may be substrates of efflux transporters, like P-gp, one of the most important mechanisms behind species differences in drug disposition in the brain can be traced back to this phenomenon, i.e., that a CNS drug is a substrate of P-gp in a given species.

Ubiquitin has several lysine residues that may be substrates themselves of ubiquitylation, leading to the formation of polyubiquitin chains.

In conclusion, there is no general rule for a variant dependent metabolism profile by cytochrome P450 2D6 indicating that the activity profile of the CYP2D6 alleles may be substrate specific, thus may be reflected in pharmacokinetics consequences for individuals.

A reason for these controversial findings could be that the regulation of PI3K p110δ and p110γ activity may be substrate specific.

This suggests that the functional effects of the UGT1A4 codon 24 polymorphism may be substrate dependent.

For both reactions, the relative ordering of the OA and TM steps is uncertain and path selection may be substrate dependent.

However, the actual rates may be substrate limited due to a lack of inputs from the Danube River – the main source of substrates.