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Such thresholds may be stochastic, differ among the population and even be a function of socio-economic characteristics and choice conditions.
Steady state can also be used to determine the time-averaged behavior of tissues, as individual cellular events (e.g. protease secretion by an infiltrated neutrophil and subsequent VEGF release) may be stochastic and transient in nature.
Either domain may dissociate first, or the sequence may be stochastic based on the individual domains' dissociation kinetics.
Alternatively, the fluctuations may be stochastic, as appears for initial Nanog expression in the embryo (Dietrich and Hiiragi, 2007).
This allows detection of candidate genes with inconsistent changes in expression, so is particularly suited to studies where changes may be stochastic.
We speculate that these differences may arise because the healing of acute injuries is a deterministic process whereas late side effects may be stochastic phenomena.
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Induced pluripotency [ 18] helps to create embryonic stem cells and, hence, a range of differentiated cell types, from differentiated adult cells but the efficiency is low and the mechanism of reprogramming may well be stochastic [ 19].
Indeed, we note that transcriptional pausing and arrest may largely be stochastic, and that it does not necessarily increase with rising gene expression levels, potentially helping to explain why the occurrence of CFSs, although typically occurring in genes, is not correlated with their transcription level (Le Tallec et al., 2013).
Depending on the particular problem under consideration and the assumptions made in solving it, the optimization problem may be deterministic, stochastic, or a combination of both.
Design of a preview compensator that may be called stochastic optimal, output feedback, preview regulator problem is reduced to the classical linear quadratic Gaussian problem by augmenting dynamics of the original system and previewed road inputs.
One factor underlying this lack of uniformity in immune response may be the stochastic nature of genetic drift acting on regulatory regions or functional genes associated with immunity.
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