Sentence examples for may be single dose from inspiring English sources

Lower dose (may be single dose) can cause severe toxicity to β cells in the pancreas which cause necrosis and then hyperglycemia occurs [2].

In addition, the twice-a-day and thrice-a-day dosed medications were more potent than once-a-day dosed medication, which may be due to single dose of large amount of drug exceeding the capability of absorption in gastrointestinal tract.

One explanation for the lack of improvement in MCC in more children in our study may be that a single dose of HS is inadequate to show an MCC benefit.

However, as peak effects may be exaggerated in single dose studies of long-acting insulin analogues and the concept of long-acting insulin is to provide continuous basal coverage, steady-state pharmacodynamic studies are probably more clinically relevant in this situation.

The plasma levels of PE extract and the accumulation of PE extract on renal tissues with the repeated daily dose may be higher than the single dose administration.

It is well established that effective administration of single agent carboplatin may be compromised by dose-limiting thrombocytopenia, which may be circumvented by the platelet sparing effect of paclitaxel.

In elderly patients on a sodium-depleted diet, a drop in GFR may be significant after a single dose of COX-2 inhibitor [9].

For instance, oxybutynin immediate release may be useful as a single dose in the evening for patients with nocturia who do not have troubling symptoms during the day.

While it is possible that such effects may be judged irrelevant for single dose studies in adults, it is nevertheless important that the whole existing database is taken into account when making judgments on the risk to volunteers, as elaborated further below.

20 With drug combinations, maximal suppression of resistant clone outgrowth was achieved at lower concentrations compared with single agents, suggesting that such combinations may be equipotent to higher dose single agents.

FCM is dextran-free and may be administered in large single doses up to 1000 mg iron either as an infusion (limited at 20 mg iron per kg body weight) or injection (limited at 15 mg iron per kg body weight) and does not require a test dose.