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Infections may be refractory because of the artificial nature of the graft.
Furthermore, patients may be refractory or may become resistant to tamoxifen treatment.
Some patients with chronic extensive alopecia areata (AA) may be refractory to topical immunotherapy.
Together these studies suggest that zinc deficiency leads to the development of depression-like behaviors that may be refractory to antidepressant treatment.
Anti-VEGF biologics are the standard of care, but may cause ocular or systemic side effects after intraocular administration and patients may be refractory.
These failures in treatment efficacy have led many to believe that symptomatic disease, including both mild cognitive impairment (MCI) and AD, may be refractory to therapeutic intervention.
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Alternatively, the genes may initially be refractory to the β3-stimulus.
50 However, children with systemic onset JIA may often be refractory to treatment with both conventional DMARDs and biologics.
Furthermore, as noted above, supplemental oxygen only benefits areas of V ˙ / Q ˙ mismatch and patients with extensive intra-pulmonary shunt may actually be refractory to this treatment.
It was not the intention of this study to duplicate this topic; rather we aimed to demonstrate that a number of GFD-adherent NRCD patients who are classified as RCD1 may not actually be refractory to dietary therapy.
As such, BMMC may be functionally refractory to release of IL-33.
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CEO of Professional Science Editing for Scientists @ prosciediting.com