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However, this restriction may be problematical itself.
Artificial neural networks have intrinsic advantages with respect to common statistical models, though the training process may be problematical.
Independent historical changes in genome architecture in diverse lineages raise a significant challenge to the idea that genome size is finely tuned to achieve adaptive phenotypic modifications and suggest that attempts to use phylogenetic analysis to infer ancestral genome sizes may be problematical.
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It may prove to be problematical.
Yet even these weak forms of paternalism may be morally problematical, and of course happiness-based policies can be less gentle than that.
Since the probe length for this assay is shorter (25 bp) than in the Illumina GoldenGate assay, the high SNP frequency may be less problematical.
Ultimately, using atomic protein models refined from low-resolution X-ray data as starting points for further studies such as drug discovery and design may well prove to be problematical or even pointless.
In a diverse society the mechanics of equality are supposed to be problematical.
"You're assuming every market would take it," Palansky said, "but it would be problematical in those secondary markets.
Stock sectors that would appear to be great bets turn out to be problematical.
And purchasing a watch on eBay could be problematical, because it is often unclear who the seller is.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com