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As dyslipidemia is an early manifestation of conditions characterized by insulin resistance and is often detectable before the development of postprandial or fasting hyperglycemia (Lewis et al. 2002), lipid concentrations may be intermediaries in the associations between POPs and type 2 diabetes.
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The observation that inclusion of IL-6 and ICAM in multivariate models (Model 2) reduced the importance of father's occupation/parental home conditions (owner-occupier status and overcrowding) as potential predictors suggests that chronic inflammation and endothelial activation may be intermediary phenotypes in the relationship between adverse childhood home conditions and poorer lung function.
As such, ATP signaling onto retinal microglia may indeed be intermediary to ionotropic glutamatergic neurotransmission and may possibly involve astrocytes, Müller cells, and neurons as the potential sources from which ATP release occurs.
In turn, the availability of these technical resources would overcome the problem of interfering with the immune system whereby P2X7 receptors may be relevant intermediaries of the response to myelin antigens in EAE.
The Dpp-expressing cells may thus be considered to be intermediaries that relay Hh signaling.
It may, however, be debatable whether it is correct to adjust for miscarriages and irregular periods when assessing the relationship between body mass index at age 20 and failing to become pregnant, as these variables may be considered intermediary.
Consequently, to further elucidate the role of ICBP90, we hypothesised that ICBP90 may be an intermediary actor in the E2F-induced TopoII α expression, and that its expression may be deregulated in cancer cells vs noncancer cells.
LOB domain protein is a key regulator of post-embryonic root initiation that is regulated by auxin [ 34, 35] and that may be an intermediary between auxin signaling and root morphology.
Note that DCM allows one to make inferences about changes in effective connections between areas, which do not necessarily correspond to direct anatomical connections but may be via intermediary regions.
Traders say that investors from China and other Asian countries may be buying through intermediaries.
Physiological senescence may be the functional intermediary between so-called longevity genes and demographic senescence.
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