Sentence examples for may be downregulated from inspiring English sources

During the progression of epithelial to mesenchymal transition both markers are downregulated [ 44] and EpCAM may be downregulated to allow epithelial cell dissociation from the tumor and cytokeratin downregulated to facilitate cell plasticity and migration [ 45].

Whereas CGRP-mediated functions may be strengthened by an increase in CGRP and functional CGRP receptors, intracellular NO signalling mediated by sGC may be downregulated, possibly by negative feedback mechanisms.

As discussed previously the Nrf2 transcription factor may be downregulated in COPD with potentially enhanced damage from ROS. Systemic inflammatory markers are also associated with an increased risk of lung cancer and there have been a number of publications in this area particularly in relation to CRP.

These results indicate that Bmi-1 may be downregulated via a posttranscriptional mechanism in Atm-/ NSCs.

However, it is still possible that some transcription factors or other proteins may be downregulated in response to MGO.

Other studies suggest that the neurotoxicity of PrP peptides is through the amplication of PrPC associated signalling pathways [63] which may be downregulated following glimepiride treatment.

These genes may be being downregulated in a translational form and the upregulation of the mRNA could be a retroactive mechanism to valance that.

These PTPs may not be expressed in the early differentiation stages represented by the leukemic blasts, or may potentially be downregulated, another interesting topic for further investigation.

NKG2D may also be downregulated by soluble ligands released from the surface of cancer cells[24], and by chronic exposure to cells expressing its ligands[25], [26], [27].

β-Adrenergic receptors may also be downregulated in patients with pre-existing cardiac failure.

63 The latter enzyme, moreover, may also be downregulated directly by fibrate therapy.