Your English writing platform
Discover LudwigSuggestions(1)
Exact(3)
Further, at the transcriptome level, the effect of radiation on gene expression may be dosage dependent.
Our study suggests that EGFL6 and MYH11 may be dosage sensitive genes involved in embryonic heart development.
HOTAIR is involved in the PRC2-mediated silencing of chromatin at HoxD loci, but its main effect in the regulation of Hox gene expression may be dosage compensation.
Similar(57)
Like many other nuclear encoded genes that function in organellar macromolecular complexes, Lhc genes may be dosage-sensitive and members in the family might have been retained collectively following the most recent WGD, to keep proper protein balance [ 53].
Polyploidization events increase the dosage of all loci, including structural and regulatory loci, controlling traits that may be genome dosage sensitive.
However, also the function of Mcph1 in the regulation of chromosome condensation may be more dosage sensitive than some of its other functions.
Retention of tandem duplications may be due dosage response in some plants.
For example, one study suggested that there may be gene dosage changes during a transition from DCIS to IDC [ 6].
A better explanation or a more likely explanation for heterosis observed in polyploids may be gene dosage effect.
The presence of a mammary phenotype in the TGF-β1+/- mice suggests that there may be pronounced dosage effects in the TGF-β system.
In addition, haploinsufficient genes (i.e. dominant disease) may be more dosage-dependent, in which case retention of paralogues may be advantageous [ 15].
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com