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A beneficial material creating these nanostructures may be DNA, with the highest specificity in the assembly and the most simplicity in their fabrications and organizations.
One potential mechanism controlling the TLR response pathway may be DNA methylation.
The direct cause of the strand bias structure may be DNA replication.
In adenosarcoma with sarcomatous overgrowth, the mesenchymal component may be DNA aneuploid whereas in adenosarcomas without sarcomatous overgrowth, it is usually DNA diploid[ 31].
Also, the presence of H2A.Z affects nucleosome mobility [ 94] and positioning [ 93] in vitro and in situ [ 95] in a way that may be DNA sequence dependent.
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Similar(51)
It has also been proposed that in mammals there is controlled DNA "repair" by transposons [ 215], which of course may also be DNA "change".
It is also worth considering that some of the initial changes may not be DNA-sequence alterations but epigenetic changes.
The nucleic acid may be either DNA or RNA and may be double-stranded or single-stranded.
Because most epigenetic modifications may be reversible, DNA methylation and histone deacetylase inhibitors can be used to induce reexpression of genes that have been silenced epigenetically.
Data suggest that all of these modes of action result from base pairing to their targets, which may be mRNA, DNA, or even a nascent transcript [1, 2].
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