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A number of ncRNAs may be curated based on the presence of PolII/PolIII promoter sequences.
However, it is expected that more snoRNA genes may be curated as the snoRNA discovery methods improve.
Gene sets may be curated [ 2], or derived from databases such as Gene Ontology (GO) [ 3] or Kyoto Encyclopedia of Gene and Genomes (KEGG) [ 4].
In such projects, not all relevant data may be curated and, due to their more transient or contingent nature, good-enough and best-effort results can be acceptable.
Annotating with an emphasis to entirely describe all phenotypes found in a disease ensures that phenotypes that may have been ignored in other annotation contexts may be curated as relevant.
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You may find reviews on the company's forums, but these could be curated by the company, with bad reviews getting deleted.
How shall all this data be curated?
A similar or identical item may have been curated in a previous curation project or appear more than once within the same curation project.
Each curator may have a different method by which they curate an article, but all curators follow strict guidelines as to what type and depth of data are curated and any inconsistencies in curation are identified in regular curator meetings.
However, the value of the items may not be fully known until they are curated.
It is worth noting that the value of an item may also change over time once it has been curated.
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