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Assessment of lung-specific markers may be challenging, especially during early disease when changes may be compartmentalized to the lung; two, samples directly obtained from the lungs as BAL or exhaled breath provide evidence for early inflammation but are still in early stages for use as biomarkers.
Our data reveal a new intracellular location for ADP-ribosyl cyclases and suggest that production of calcium mobilizing messengers may be compartmentalized.
It has been proposed that the enzymes of nucleotide biosynthesis may be compartmentalized or concentrated in a structure affecting the organization of newly replicated DNA.
Even if it is not a proof of co-localization with ribosome, Hfq co-localization with the ribosomal marker S1 near the inner cytoplasmic membrane as shown here suggests that translation of a class of transcripts that code for membrane proteins may be compartmentalized in this sub-membrane region.
This pattern strongly suggests that FITC-conjugated CPE peptide may be compartmentalized after entry into tumor cells.
Recent investigations have suggested that iNOS activity may be compartmentalized at the site of infection and parallels expressions of inflammatory cytokines [ 7].
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Among other things, the applicability of a NADH/NAD determined for the whole cell to a specific biochemical reaction that may well be compartmentalized, or which may be proceeding under non-equilibrium conditions, remains to be demonstrated.
While mutation load is individualized, DNA damage may not be compartmentalized to one site.
There is some evidence that metabolic pathways of lacustrine bacterioplankton may simply be compartmentalized between the main phyla (Actinobacteria, Betaproteobacteria, Alphaproteobacteria, and Bacteroidetes) (Debroas et al. 2009).
It is known that HIV-1 can be compartmentalized in the brain [ 32] which could mean that it may be more directly relevant to correlate the cognitive defects to brain- or CSF-derived HIV-1 sequences than to plasma.
But there are some things which cannot be compartmentalized.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com