Some of these functions may be cis-regulatory [ 28] or the result of regaining of transposon activity, known as domestication [ 24, 41- 46].
This suggests that RETN expression may be cis-regulated, meaning there are variants in or near the RETN gene that influence the abundance of its mRNA [ 38].
These results show that one or more plasmid replication origins (ARS elements) are contained within R1 and suggest that there may be cis-acting sequences outside of R1 that can suppress origin activity.
In many cases, lnc-RNAs may act as guides and aid in directing the effector molecules, which may be cis-regulators, transacting proteins, or TFs, to their respective binding sites [ 40].
Another study showed that the presence of the risk allele in intron 1 is associated with increased levels of the FTO transcript, suggesting that there may be cis-regulatory site that regulates FTO in intron 1 [ 28].
This might suggest that in addition to trans-interactions between Ft and Ds in neighbouring cells, there may also be cis-interactions between Ft and Ds molecules in cell junctions, a view supported by previous experimental reports (Matakatsu and Blair, 2006; Sopko et al., 2009).
2) Some staples may be in cis and others trans.
QTug.sau-3B may be a cis regulatory factor of Ttam-3B or a trans regulatory factor of Ttam-3A or Ttam-3D affecting Ttam expression.
The FIRE analysis for the life cycle regulated genes identified overrepresented motifs of known function (i.e., TGCATG, GCTAGC, and ACCA(A/C/T TG) indicating that newly identified motifs may be functional cis elements.
So for example, while a bisexual cis woman may be attracted to cis men and women, I am attracted to cis people, trans people, demigender people, and genderfluid people, to name a few.
