Sentence examples for may be blockade from inspiring English sources

Collectively, these observations suggest the primary role of IgG4 anti-NF155 antibodies may be blockade of interactions between NF155 and Caspr/contactin-1, leading to conduction failure.

The mechanism may be blockade of CB1 receptors by rimonabant leading to increased production of adiponectin, which would result in reduced abdominal fat deposition, and hence lower cardiovascular risk (Després et al. 2005a; Van Gaal et al. 2005).

Given that the ETA KO phenotype is very mild, it may be that blockade of ETA outside of the nephron may also be involved in ETA antagonist-induced fluid retention.

In this context, our observation that 5-HT6R administrationincreaseson increases PVH neuronal activation may be via blockade of 5-HT action on inhibitory ARC AgRP/GABA neurons, promoting the disinhibition of downstream anorectic PVH neurons.

Therefore, therapeutic strategies for SSc and some other fibrotic disorders may be designed by blockade of HSP47 expression, the downstream effector of TGF-β signaling, to ameliorate fibrosis.

The decrease in LTP caused by cocaine at high concentrations may be due to blockade of sodium channels [31].

Not only infectious diseases but perhaps autoimmune diseases also may be approached by blockade of TLR pathways.

This inhibitory effect may be correlated to blockade of STAT3-regulated cell cycle genes or anti-apoptotic genes.

This may be explained by blockade of RANKL/RANK interactions other than those involved in osteoclastogenesis, such as the interaction of T cells with dendritic cells [ 44].

DIDS also reduced the excitation junction potentials (Fig. 4C), which may be due to blockade of P2X receptors, as suggested previously [ 2].

The antiemetic effect of promethazine may be due to blockade of dopaminergic receptors in the chemoreceptor trigger zone (CTZ) of the medulla.