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Some lessons from the ongoing endeavor to develop FLT3 inhibitors may be applicable to the development of other targeted agents for AML.
In this review, we discussed the recent advances in anti-PRRSV immunity and vaccinology, the recent progresses in PRRSV vaccine development particularly the reverse genetics system-based vaccine development, and provided a perspective on potential novel strategies and approaches that may be applicable to the development of the next generation of PRRSV vaccines.
Thus, it was identified both that some flexibility in the interpretation of the existing guidance would be needed and that several regulatory principles already in place for the development of cellular and autologous therapeutics may be applicable to the development and testing of recombinant individualised vaccines (Britten et al, 2013).
The identification of sequential changes in DNA methylation during progression and metastasis of lung adenocarcinoma, and the elucidation of their interplay with genetic changes, will broaden our molecular understanding of this disease, providing insights that may be applicable to the development of targeted drugs, as well as powerful markers for early detection and patient classification.
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This array was chosen to identify genes in signal transduction pathways that are influenced by high ω-3 fat diet and that may be applicable to cancer development.
may be applicable to both the Department and commercial entities.
The successful adaptation suggests that the strategy and materials may be applicable to detecting/monitoring other medically significant molecules via sensor development.
This framework highlights interactions between SOC and soil development, which may be applicable to other soils where organic inputs interact with the products of chemical weathering.
As such, this combined approach may be applicable to facilitate anti-cancer target discovery and drug development.
In addition to the current GRRAS recommendations, we suggest the inclusion of additional guidelines for test set development that may be applicable to other studies.
The development of drugs targeting DDR pathways may be applicable to improve radioresistance and chemoresistance of HCC and further prolong their survival.
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