Investigators are able to participate in international collaborations, contribute to the advancement of therapies and scientific progress, increase skill levels of themselves and their teams, may augment income and may experience increased prestige and credibility.
53 Thus, iron liberated in the lesions may augment demyelination and neurodegeneration, and the observed overall iron loss in the NAWM may be both protective against inflammatory attacks and detrimental by reducing the capacity of the MS brain for remyelination and tissue repair.
Increased GLP-1 may augment diuresis and natriuresis by inhibiting sodium reabsorption from the proximal renal tubule [ 31].
Furthermore, PRF may augment noradrenergic and serotonergic descending inhibitory systems within the spinal cord, which afforded an analgesic effect in an inflammatory pain model [ 21].
These findings are supported by studies showing that c-MYC may augment IR -and chemotherapy-induced apoptosis [ 9, 11, 16, 17].
Access to web-based information and support may augment clinical interventions and provide heightened convenience and anonymity for families in securing needed information and potential peer support.
In this study, we demonstrate that treatment with either cisplatin or paclitaxel can also enhance expression of both G-CSF and G-CSFR, potentially via NF κB activation, which may augment STAT3 activation and possibly contribute to chemoresistance.
While the cDC are capable of producing significant levels of IL-12 that would enhance IFNγ production from T and NK cells, the pDC preferentially produces type I IFN that may augment NK cell and CD8 T cell differentiation into a cytotoxic phenotype [28].
Medical therapies that lower pulmonary vascular resistance may augment cardiac output and improve long-term outcomes.
Studies of response assessment have shown that assessment of heterogeneity is feasible (Fig. 5), may augment response assessment, and is a predictor of response [24, 27, 28].
