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In fact, these regulatory elements may associate insulin with changes in outflow facility.
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120– 122 Expression levels of leptin and adiponectin are also reduced, which may contribute to associated insulin resistance.
Insulin resistance has also been described in patients with RA and may associate with systemic inflammation [ 44].
To our knowledge, this is the first evidence that intestinal inflammation is an early consequence of HF diet which may contribute to obesity and associated insulin resistance.
To determine whether a DNA-based gut microbial profile may be associated with insulin action, we performed a DNA-DGGE on the cecum (appendix) contents from 8 insulin-resistant (IR) and 8 insulin-sensitive (IS) subjects (all obese; 7 women and 1 man in both groups) comparable in age and body mass index (BMI).
Dyslipidemia in the obesity may be associated with insulin resistance [ 37- 40].
Previous studies have suggested that serum IGFBP-7 levels may be associated with insulin resistance in type 2 diabetes (T2D).
Several authors have recently reported that resistin, a novel adipokine, may be associated with insulin resistance in HIV patients.
In fact, lipotoxicity by deposition of triglycerides and free fatty acids may be associated with insulin resistance and beta-cell dysfunction [ 36, 37].
The correlation between IGFBP-7 and IGFBP-1 suggests that low IGFBP-7 may be associated with insulin resistance in T2D.
One cannot, however, discard the hypothesis that longer exposure to high fructose intake may be associated with insulin resistance, possibly secondary to increased body fat mass.
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