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While some advantages, such as lack of dementia, appear late in life, others may appear early only to disappear thereafter.
Furthermore, maturation of immunocompetence in fish develops quite late although both lymphoid organs and T- and B-lymphocytes may appear early in embryogenesis [1].
Such differences may appear early, even before the gonads have developed, highlighting the important role of the sex chromosomes [39], [40] (reviewed in [41]).
Other than macules, neurological (dysesthesia, motor disorders) signs may appear early on or be observed at a late stage in the progression of the disease [ 14].
Although neurofibrillary degeneration may appear early in life [ 9], aging is one major factor for the development of AD-related neuropathology.
However, the development of IgE-ab to aeroallergens may appear early in life, in particular among children with asthma [ 7– 10].
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Headache may appear earlier in the young patients.
Symptoms may appear earlier under conditions of ideal temperature and plant growth.
However, complications may appear earlier and delivery may be a problem due to fetal prematurity.
Another option is that RDW is an earlier marker of prognosis, and it may appear earlier in the complex process of anemia than low levels of hemoglobin.
20 The effects of behaviour to lose weight may appear earlier in annual changes and then be seen in the mean body mass index later.
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