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However, such warming may alter vascular reactivity and induce hypotension [11].
However, such warming may alter vascular reactivity and induce hypotension [ 11].
There is mounting evidence that statin therapy may alter vascular atherosclerosis and reduce cardiovascular events, including myocardial infarction, stroke, and death [ 13, 14, 32].
In contrast, persistent defects in oxygen delivery to the tissues during decreased flow or hypovolemia may alter vascular and cellular metabolism.
Although the exact mechanism promoting atherosclerosis in RA remains to be defined, chronic inflammation may alter vascular endothelial biology to a pro-thrombotic/pro-atherogenic state [ 54].
As factors such as age or medication may alter vascular function, it is essential to account for changes in neurovascular coupling when investigating neurocognitive functioning with fMRI.
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Lethal toxin may also alter vascular smooth muscle function [30].
ROS may directly alter vascular function or cause changes in vascular tone by several mechanisms including altered NO bioavailability or signaling [ 35].
Hyperlipidemia and oxidation of low density lipoprotein (LDL) induce vascular smooth muscle cell growth [ 5] and hyperlipidemia may alter the vascular response to vasodilators [ 6].
Flow may determine vascular growth in the fetal cardiovascular system and thereby a reduction in flow may alter later vascular behaviour [ 120].
Also, repeated microembolisms may alter downstream vascular resistance (reviewed in [ 45]).
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