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Several studies suggest that Nrf2 may alter susceptibility to atherosclerosis.
Epidemiologic evidence suggests that chronic stress may alter susceptibility to air pollution.
These immunologic changes may alter susceptibility to and severity of infectious diseases in pregnant women.
Studies have shown that polymorphisms in genes related to oxidative stress may alter susceptibility to air pollution as measured by biomarkers of endothelial and vascular function [ 12- 16].
The vast majority of genes associated with xenobiotic metabolism and transport exhibit decreased expression compared to the adult which may alter susceptibility to environmental chemicals in the fetus and neonate.
The possibility that redistributions of lymphocyte phenotypes may alter susceptibility to infections or inflammatory diseases in otherwise healthy persons, particularly small children, is worthy of investigation in its own right.
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21 22 Genetic variants of CLDN1 may further alter susceptibility to HCV infection 23 and contribute to atopic dermatitis.
Limited but growing epidemiologic evidence indicates that psychological stress may also alter susceptibility to physical exposures, such as air pollution.
This motivation may not hold for secondary variants, but our approach is to offer them the opportunity to learn secondary and actionable variants that may substantially alter susceptibility to, or reproductive risk for, disease.
Third, changes in gene expression programmes in mammary cells after pregnancy may alter the susceptibility of the cells to transformation.
No change in PrPC levels are seen in Fkbp9 cells; however, it is possible that Fkbp9 isomerase activity may alter the susceptibility of PrPC to conversion.
More suggestions(15)
may alter bone
may prompt susceptibility
may alter salt
may alter function
may enhance susceptibility
may alter transpiration
may affect susceptibility
may alter muscle
may be susceptibility
may predict susceptibility
may alter codon
may underlie susceptibility
may create susceptibility
may reduce susceptibility
may influence susceptibility
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