However, following a cancer diagnosis, patients experience a dramatic change that may alter their internal values, leading to a shift in response for the assessment of health [ 27].
Complex interactions between chemicals, endogenous or exogenous hormones, and their natural ligands and receptors may alter the internal homeostasis of the estrogenic environment of mammary tissue, leading to malignant transformation and cancer.
It may limit, however, the speed of the response since environmental changes will alter internal characters (e.g. growth rate) only after a delay (e.g. when the intracellular pool of nutrient is diminished).
Echinoderms and other invertebrates adjust internal pH through accumulation of bicarbonate ions [42], which would alter internal calcite conditions.
Such cells may alter their orientation, shape, internal constitution, contraction, migration, adhesion, synthesis and degradation of extracellular constituents, or even their life cycle in response to perturbations in mechanical loading (Zhu et al. 2000).
Additionally, other types of internal states may alter our perception and/or preferences for sweets.
This alteration in the perceived salience of external events, and the corresponding reallocation of attention towards them (and away from internal signals), may alter the weightings applied in the process of cue integration.
According to this report, the current results suggest that POEE, by reducing ATP-mediated Ca2+ release from internal Ca2+ stores, may alter NF-κB-independent signal pathways.
1 Human skin is continuously exposed to internal and external influences that may alter its condition and functioning.
It is a well-known phenomenon that experimental conditions may alter the expression of genes that are candidates for internal controls[34], [53], [54].
