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Exact(14)
SNPs in the proximal promoter may alter expression levels of the transporters by affecting the rate of transcription.
We propose that, during pituitary development, the 18q rearrangement may alter expression of 18q genes or of X chromosome genes that are translocated next to the HCNEs.
The RD23 deletion in FTNF002-00 maltertexpressioniof of the xenobiotic response element family transcriptional regulator, given the proximity of the two.
Our documentation of induced expression of mRNA in vivo of only a subset of genes identified by IVIAT (and not the complete set) is also not unexpected, since mRNA quantity is only one of a number of variables that may alter expression or display of a given protein.
Though our strongest haplotype signals span the gene (∼3 kb) rendering it difficult to narrow the association to a causal variant, to facilitate identifying variants/mutations in AQP5 that may alter expression of AQP5, the non-synonymous SNP in exon 4 of AQP5, which results in an amino acid change (Asn to Lys) was created in a human-AQP5 plasmid using site-directed mutagenesis.
We investigated whether cell passages may alter expression of XIST, KDM5C, and KDM6A genes.
Similar(46)
Although none of the sequence changes results in a direct coding change to the DAT protein, it is plausible that they may alter expression-related processes such as transcription or splicing efficiency.
The microsatellite identified within the promoter region in this study may also alter expression of the equine OAS1 gene.
In fact, multilocus genetic control and epigenetic effects may actually alter expression in many apomictic plants (Curtis and Grossniklaus, 2007; Vijverberg and Van Dijk, 2007).
In addition, differences in cytokine and growth factor expression may alter CXCR3 expression, as tumor necrosis factor (TNF -α downregulaTNF -αCR3 expression [ 38].
We speculate that changes in C2GnT1 and C2-O-sLeX expression may alter the expression and function of other adhesion molecules on cancer cells or regulate components of the extracellular matrix known to participate in invasive events.
More suggestions(15)
may upregulate expression
may have expression
may alter salt
may alter transpiration
may prevent expression
may exhibit expression
may induce expression
may affect expression
may alter contact
may regain expression
may promote expression
may show expression
may find expression
may increase expression
may cause expression
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