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Pulmonary exacerbations (PEs) are defined episodes of acute worsening and a key clinical efficacy measure in CF. Our hypothesis was that acute antibiotics given for illnesses not meeting the PE definition may alter estimates of treatment effect that do not account for this antibiotic use.
Furthermore, the use of purified epithelial populations, rather than mixed cell isolates, may alter estimates of stem/progenitor cell potential.
Thus, measuring drug concentrations close to the time of a filter change may alter estimates of clearance and should be avoided.
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The Cox adjustments at events may unduly alter estimates of DSS at the end of the study period when there are few patients left.
Here we are using a single method of phylogenetic construction, but there are other methods that may alter PD estimates.
Factors that may alter future estimates of case-fatality rates, reasons for heterogeneity in doubling times among countries, and implications for the control of SARS are discussed.
Because SIF is positively associated with subclinical atherosclerosis and/or cardiovascular disease mortality, Similarly, because SIF has been proposed as an alternative noninvasive screening tool in comparison with fasting glucose levels in identifying individuals with prediabetes or type 2 diabetes mellitus, adjusting for caffeine and/or coffee intake may alter prediction estimates.
DNA quantities have to be really accurate to assure that each sample in the pool provides equal quantities of DNA in order to minimize technical errors that may alter the estimated methylation levels [ 14, 20].
First, variations in scan parameters in bevacizumab-treated patients before and/or after therapy may have altered estimates of traditional CBV metrics.
The inclusion of individual covariates can alter estimates dramatically.
Because of the difficulties of long-term field experimentation in the region, not all observed events can be considered equally well recorded; in particular, detection of exogenous water inflow occurrences that may alter Wankama runoff estimates is needed.
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