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These viruses may alter components of PML-NBs, regulate expression and localization of PML protein, and even disrupt PML-NB structure (recent review in [ 131]).
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Physical interferents, including blood hemolysis (HEM), icterus (ICT) and lipemia (LIP) may alter the component concentrations.
This reversal of control relationship suggests that seawater intrusion may alter which ecosystem components regulate the distribution of energy matter for reactive nitrogen species in estuaries.
Thus, although polymeric materials offer great potential for new vaccines, the intrinsic immune characteristics can hinder rational vaccine design and translation because the role of the carrier itself may alter how other vaccine components or signals (e.g., antigens, adjuvants) are processed.
This component may alter the behavior of this mouse strain when added to urine.
First, it may alter the binding to component of the basal transcription machinery, thus decreasing transcriptional activation.
The most important drawback and criticism levied against studies based on BM chimaeras is that the irradiation protocol required to eliminate the host's immune component may alter the permeability of BBB, thus allowing for greater leucocyte infiltration than would otherwise occur in the absence of irradiation.
Temporomandibular disorders lead to parafunctional activity that may alter bone remodeling of mandibular components.
This is particularly important when IAPs are considered transformers (or drivers of ecological change) because they may alter both subtle and obvious components of ecosystem functions and services, e.g. by being excessive users of nutrients, donors of limiting nutrients, fire promoters/suppressors or salt accumulators/redistributors (Richardson et al. 2000; Richardson and Gaertner 2013).
26 27 These supplements have phytoestrogen components that may alter oestrogen levels or activate oestrogen receptors as either proestrogen or antioestrogen.
Although demonstration of a causal link requires further investigation, we speculate that injury-associated platelet activation and subsequent fibrinogen binding may alter platelet ability to recognize bacterial components, some of which are ligands of αIIbβ3 [35] 35], and affect their ability to alert and recruit cells of the immune system [8].
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