Besides mapping of phylogenetic relationships to other strains, we find that the sequence variation in the new strain does not seem to affect the drug binding site but may very well alter common epitopes.
But the cultural historian Nicholas Fox Weber, a contributor to The New York Times, is at work on an exhaustive biography (for Alfred A. Knopf) that may alter the common perception of the architect as an egotistical curmudgeon.
Similarly, complex, low odd-ratios haplotype associations patterns may reflect heterogeneous routes to alter common pathways.
Moreover, the promising results obtained in both sarcoidosis and psoriasis patients after application of anti-TNF alpha agents (e.g. infliximab, adalimumab, etanercept) further support this hypothesis, since these therapeutic agents may alter pathogenic mechanisms common to both disorders [ 11, 13- 15].
Mitochondrial gene/genome rearrangements may alter the expression of common mitochondrial genes coding for proteins involved in respiration/ATP synthesis, affecting ATP production and/or other processes within mitochondria.
In the present report we review possible common mechanisms that may alter tau expression and function, in particular in relation to the effect of certain overexpressed DS-related genes, using cellular models of human DS.
Common gene variations may alter the heart rhythm in slight ways that don't cause problems under normal conditions but may predispose people to sudden death during a heart attack or if they take certain drugs that affect heart rhythm.
Table 1 describes common factors that may alter pharmacokinetics of antibiotics in critically ill patients.
The discrepancy of MSCs function between in vitro and in vivo conditions, implies that a common endogenous stimulus may alter the in vivo performance of MSCs and that the immune privilege ascribed to MSCs may be susceptible to the influence of the microenvironment.
Common polymorphisms in DNA repair genes may alter protein function and the possibility to repair damaged DNA.
