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It may also specifically promote proliferation by enhancing activity of the c-Myc oncoprotein [ 49], in contrast to inhibition of cell cycle progression by HIF-1α counteracting c-Myc transcriptional activity [ 50].
Fluorescent probes may also specifically target a labile pool of the metal ion of interest, or those occurrences of the metal ion in which it may be competitively exchanged.
This has been linked to weight loss through the associated elevations in REE (Staal-van den Brekel et al, 1995) and declines in dietary intake (Wigmore et al, 1997), but may also specifically lead to the depletion of FFM (Simons et al, 1999).
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It should therefore be considered that alterations in mGluR5 mRNA are not only brain region-specific, but may also exist specifically in selective neuronal populations in the diseased brain, and analyses of total neuron populations may therefore conceal pathological alterations.
Mutations in ubiquitination related proteins may also affect specifically spermatogenesis through their testis specific interacting partners [ 36].
Based on the findings of in vivo studies that showed core particles binding specifically to the HBV pregenome and genome, we hypothesized that HBc may also bind specifically to certain human gene promoters, either through its C-terminal functional domain or its N-terminal assembling domain.
Internet use may also lead specifically to dopamine release in the nucleus accumbens [ 8], one of the reward structures of the brain specifically involved in other addictions [ 9].
They may also search specifically for images, videos, or news articles or for names of Web sites.
mAbs may also bind specifically to a non-intended target and cause alteration of PK/PD and toxicity profiles.
Similarly, other 2D-DIGE biomarker candidates may also require specifically tailored assays for accurate, high-throughput measurement.
It should also be noted that the ant orthologs of the A. mellifera c-minus clade (e.g. HsalObp7 and CfloObp7, no phylogenetic relation to CbirObp7), which are moderately expressed in the antennae of H. saltator and C. floridanus, may also be specifically expressed in the antennae of ant species with functional copies of these genes.
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