Presumably, this result is due to the severing action of sAB-4 that would disassemble F-actin nuclei immediately upon polymerization, although sAB-4 may also sequester the G-actin monomers to block polymerization.
It therefore remains an interesting possibility that nucleolin (with RPA) may also sequester Y RNAs under stress conditions in the intact cell, thus inhibiting the function of Y RNAs in DNA replication under these conditions.
The immunoglobulins may also sequester certain activated complement components and block the activity of F c receptors.
PKA phosphorylates Gli3 prior to processing by the ubiquitin-proteasome pathway (52), whereas Sufu inhibits the transcriptional activity of Gli activators in the nucleus and may also sequester Gli in the cytoplasm (49, 50, 53, 54).
Other studies have also shown that E and N-cadherin interactions may also sequester β-catenin levels in HSCs, and down modulate the expression of Wnt targets of self-renewal, like Myc.
In addition, the high sorption capacity of nanoparticles that is used to remove organic and inorganic pollutants from groundwater may also sequester and transport other pollutants in the environment (Nowack 2008).
