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This result suggests that overexpression of eat-6 may also perturb ACh synaptic transmission at the locomotory NMJs.
We were interested whether the gene trap mutation may also perturb meiosis and in particular meiotic chromosome condensation.
Taken together, these results indicate that cancer predisposition alleles that are DNA damage sensitizing may also perturb the ability of the DNA repair pathways to elicit CSR.
Theoretical approaches then suggest that mutations provoke dynamic alterations of the native state and that, by modifying the conformational preferences, may also perturb its molecular recognition properties.
The manipulation of cells during their purification may also perturb their methylation profile and gene expression.
Epigenetic variation between hESC lines may also perturb X chromosome inactivation.
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Based on the Abd-B expression observed in the Abd-BT2N insertion line, we hypothesized that the expression pattern of the endogenous Abd-B gene from the Abd-BΔPTE-UP allele may also be perturbed.
These studies suggest that the afferent pathways subserving bladder/bowel function in rodents may also be perturbed by ageing.
ER protein folding may also be perturbed by adverse conditions encountered in the host such as mammalian body temperature, oxidative stress, hypoxia and nutrient limitation [ 13].
Since studies in other tumor types have shown that the AKT pathway may also be perturbed by lapatinib, we analyzed p-AKT levels before and after treatment.
Moreover, we found cre-1 expression levels to be elevated when cells suffered ER stress, suggesting that the intracellular glucose homeostasis may also be perturbed under these conditions.
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