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We realize that the nestin promoter-driven Cre may also delete LRP6 in neural stem cells/progenitor cells as nestin was originally described as a neuronal stem cell marker expressed during central nervous system development.
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27 Not all deletions may involve ND4 and ND1, although rarely, may also be deleted.
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Additionally, immunization with recombinant VP2 was also defective in mice expressing the complete VP2 capsid protein, suggesting that other epitopes from VP2 may also be deleted.
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