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Alleviation of this metabolic checkpoint in type 2 by p53 mutations may allow progression to eosinophilic ChRCC, indicating that they represent higher risk.
The results from this case study suggest that diffusion tensor imaging may allow progression of the disease to be quantitatively measured and may be able to play a role as a surrogate marker in clinical trials.
Delay in multidrug resistant tuberculosis treatment may allow progression of the disease and affect the attempts to curb transmission of drug resistant tuberculosis.
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During the process of somatic tumor evolution, a specific pattern of chromosomal losses and gains present in the majority of CCLs may restrict acquisition of chromosomal rearrangements essential for further tumor progression while specific mutations only present in a subset of all CCL may allow tumor progression through all stages.
These specific features may allow the progression of the replicative helicase despite the impossibility to unwind the two parental strands at the psoralen ICL.
However, previous studies have shown that induction of the DNA damage response pathway is an important early event in determining whether precursor lesions will develop into malignancies [ 25], and those authors suggest that mutations which disrupt the DNA damage response may allow tumor progression.
These alterations sustain disease and allow progression; mechanistically, they may also enable development of hormone therapy resistance.
We now hypothesize that in 2006 the patient was infected with A. lentulus, which could not correctly been identified morphologically, and that inefficient antifungal therapy for the causative A. lentulus may have allowed progression.
To allow progression three levels of difficulty are defined.
For patients receiving chemotherapy, earlier assessment of response may provide either reassurance that the expenditure and any attendant toxicity are worthwhile, whereas lack of response or progression may allow a change in treatment before significant progression or toxicity have accrued.
The identification of the potential AKI progression may allow us to initiate early interventions (e.g., more invasive monitoring and RRT) before the development of life-threatening complications.
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