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In silico simulation of optimal treatment regimens may allow optimization of experimental and, later, treatment parameters.
HP can affect the functionality of protein and carbohydrate molecules often in unique ways, which may allow optimization of food manufacturing processes and production of novel foods.
Therefore, an understanding of the features of MNPs that influence their interaction with macrophages may allow optimization of their properties for enhanced drug delivery.
The hydrated hydrophobic cavities may allow optimization of the sheet association and constitute a typical feature of fibrils, in addition to the tight sheet-sheet association.
This may allow optimization of the location choice for biopsy, which is still the gold standard for diagnosing idiopathic interstitial pneumonias and currently done with the help of attenuation-based HRCT (Gross and Hunninghake, 2001).
Consistent with this concept, the ratio of red to far-red light was tested, as a steady-state equilibrium of active phytochrome and input through phytochrome A may allow optimization of pigment accumulation.
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For example, exploring topoisomerase II isozyme selectivity, investigating the sensitivity and resistance of topoisomerase II mutants to voreloxin and analogs, and possibly mapping the sites of drug enzyme interaction may allow further optimization of topoisomerase II-targeting therapeutics to enhance clinical benefit.
Computer modeling (21– 23) of the profiles obtained here may allow for optimization of algorithm performance and should lead to improved outcomes in subsequent clinical studies.
Such approach may lead to simultaneous removal of toxic metals, organic loads and other inorganic impurities, as well as allow optimization through development of resistant species.
Multivariate, algorithmic approaches allow optimization of combinations of clinical variables to predict outcome.
The demonstrated approach may allow a framework for optimization of oral drug therapy post-bariatric surgery.
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