Is it possible that specific biomarkers exist that may allow dynamic modulation of DBS specific to these impairments as well?
Our results suggest that selective targeting of H-Ras and N-Ras may allow specific modulation of T-cell ROS production and integrin activation in RA T lymphocytes.
Such algorithms may allow the modulation of the "shared control" between the neural interface (i.e., the user's intention) and the low-level control for different robotic devices and different subjects.
Thus, the determination of individual gene expression patterns may facilitate the selection of the best medication or, more ambitiously, may allow directed modulation of (individually) selected pathways/complexes instead of broad suppression of inflammation by anti-inflammatory/anti-rheumatic drugs [ 84].
Therefore, multi-CAM targeting may aid the optimization of some therapeutic nanocarriers, where the combination and multiplicity of the affinity moieties utilized allow modulation of targeting performance.
In addition to the MYBs that are part of the activation complex, distinct R2R3- and R3-MYBs with a repressive action have been identified that may allow for feedback modulation of the amount of anthocyanin produced [ 10- 14].
High-definition transcranial direct current stimulation (HD-tDCS) may allow more specific neural modulation than conventional-tDCS.
However, the use of alternative AAV serotypes or capsid variants, AAV capsid decoys, pharmacological immune modulation, and/or plasmapheresis treatment may allow AAV transduction in the face of pre-existing antibodies.
Treatments directed at Wnt and Notch signal pathways may allow for regulation of EMT in tumors and modulation of CSCs.
The PSY1R might integrate growth promotion and defense signals leading to modulation of cellular plasticity, and may allow the cells to adjust towards environmental changes.
