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From these results, we conclude that some nonessential trace elements may affect vitamin D metabolism, and this relationship deserves further study.
Second, conditions that may affect vitamin D levels, such as treatment in cancer patients or comorbid conditions in primary care patients, were not accounted for in the analysis.
All of these considerations are true in critical illness, but there are even more potential confounders such as inflammation and acute fluid loading that may affect vitamin D concentrations.
Models adjusted for factors that may affect vitamin D levels (AER, total vitamin D intake, and total calcium intake) were also run to examine the precision of our estimates.
Fine mapping around the region with strong signals of association in our AAs may help identify other variants that show stronger association and find functional variants that may affect vitamin D synthesis and metabolism.
25(OH D half-life may be useful as a biomarker of vitamin D metabolism to investigate environmental or physiological factors that may affect vitamin D usage and to better assess vitamin D requirements.
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Renal impairment may also affect vitamin D metabolism and result in a reduction of vitamin D levels, which contributes to osteoporosis in the elderly (Compher et al 1998).
Malabsorption syndromes may also affect vitamin D bioavailability regardless of sunlight exposure or dietary intake, as well as conditions such as obesity or renal insufficiency, which may interfere with vitamin D extraction or conversion to its active form.
This survey highlights some current trends and conflicts in attitudes and behaviour toward sunlight exposure, and knowledge of vitamin D, that may adversely affect vitamin D status in middle-aged and elderly Hong Kong women – a population at greater risk of poor bone health and vitamin D inadequacy.
Genetic factors that may affect the Vitamin D levels in body were also explored for their link with diabetes.
A number of factors may affect serum vitamin D3 production in skin such as skin color, season, altitude, time of the day, and amount of sun exposure.
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