Sentence examples for may affect synaptic from inspiring English sources
NALCN channel may affect synaptic transmission.
On the other hand, the presence of a strong Ca2+ chelator in the presynaptic neuron may affect synaptic release [27].
Taken together, our approach with aged mice elucidates at the molecular level how A53T-SNCA overexpression in the nigrostriatal projection may affect synaptic strength and integrity.
In summary, a down expression of actin may affect synaptic efficacy and ultimately impair the molecular machinery that is responsible for learning and memory.
We thus hypothesize that xCT may affect synaptic plasticity developmentally through modulating extracellular glutamate.
Mitochondria have been shown to be concentrated in both the presynaptic nerve terminal and the postsynaptic endplates in muscle, indicating that a decline in mitochondrial bioenergetic function may affect synaptic transmission and result in a loss of NMJ innervation.
In addition, they may also affect synaptic plasticity by regulating downstream signal transduction pathways.
Furthermore, in view of the important roles of ubiquitin system in synaptic growth and function, downregulation of Nedd4 may also affect synaptic growth and plasticity, contributing to altered brain function.
They point to earlier animal experiments showing that fetal or neonatal testosterone levels in humans may first affect synaptic density, neuronal activity, or neurochemical content during early BSTc development, and that "[c]hanges in these parameters could affect the development of gender identity but not immediately result in overt changes in the volume or neuronal number of the BSTc".
Furthermore, astrocytes regulate synaptogenesis and may directly affect synaptic connectivity by releasing neuromediators such as ATP and/or d-serine and by regulating the level of extracellular glutamate (Pfrieger and Barres, 1997; Anderson and Swanson, 2000; Ullian et al., 2001; Eroglu et al., 2008; Stipursky et al., 2011).
Understanding more about how this local control of protein production works within neurons may provide new insights into diseases that affect synaptic plasticity.
